Advanced glycation end products promote proliferation and suppress autophagy via reduction of Cathepsin D in rat vascular smooth muscle cells

Abstract

Autophagy is closely involved in vascular smooth muscle cell (VSMC) function, but little is known about the association between advanced glycation end products (AGEs) and autophagy and its role in AGEs-induced proliferation and migration of VSMCs. The current study investigated the effects of AGEs on the phenotypic modulation and autophagy of VSMCs, as well… (More)
DOI: 10.1007/s11010-015-2338-x

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@article{Ma2015AdvancedGE, title={Advanced glycation end products promote proliferation and suppress autophagy via reduction of Cathepsin D in rat vascular smooth muscle cells}, author={Mingfeng Ma and Xiaofan Guo and Ye - In Chang and Chao Li and Xin Meng and Si Li and Z Du and Hua-Qin Wang and Yingxian Sun}, journal={Molecular and Cellular Biochemistry}, year={2015}, volume={403}, pages={73-83} }