Advanced glycation end-products produced systemically and by macrophages: A common contributor to inflammation and degenerative diseases.

@article{Byun2017AdvancedGE,
  title={Advanced glycation end-products produced systemically and by macrophages: A common contributor to inflammation and degenerative diseases.},
  author={Kyunghee Byun and Yongcheol Yoo and Myeongjoo Son and Jaesuk Lee and Goo-Bo Jeong and Young Mok Park and Ghasem Hosseini Salekdeh and Bonghee Lee},
  journal={Pharmacology & therapeutics},
  year={2017},
  volume={177},
  pages={44-55}
}
Advanced glycation end products (AGEs) and their receptor have been implicated in the progressions of many intractable diseases, such as diabetes and atherosclerosis, and are also critical for pathologic changes in chronic degenerative diseases, such as Alzheimer's disease, Parkinson's disease, and alcoholic brain damage. Recently activated macrophages were found to be a source of AGEs, and the most abundant form of AGEs, AGE-albumin excreted by macrophages has been implicated in these diseases… CONTINUE READING
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