Advanced glycation end products-induced apoptosis and overexpression of vascular endothelial growth factor in bovine retinal pericytes.

@article{Yamagishi2002AdvancedGE,
  title={Advanced glycation end products-induced apoptosis and overexpression of vascular endothelial growth factor in bovine retinal pericytes.},
  author={Sho-ichi Yamagishi and Shinjiro Amano and Yosuke Inagaki and Tamami Okamoto and Kohachiro Koga and Nobuyuki Sasaki and Hiroshi Yamamoto and Masayoshi Takeuchi and Zenji Makita},
  journal={Biochemical and biophysical research communications},
  year={2002},
  volume={290 3},
  pages={973-8}
}
The influence of advanced glycation end products (AGEs) on apoptotic cell death and vascular endothelial growth factor (VEGF) gene expression in cultured bovine retinal pericytes was investigated. When pericytes were incubated with three immunochemically distinct AGEs, which were prepared in vitro by incubating bovine serum albumin with glucose, glyceraldehyde, or glycolaldehyde, apoptotic cell death and DNA ladder formation were significantly induced. The cytopathic effects of glyceraldehyde… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 73 extracted citations

Advanced glycation and retinal pathology during diabetes.

Pharmacological reports : PR • 2005
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…