Advanced glycation end products and vascular structure and function

@article{Soldatos2006AdvancedGE,
  title={Advanced glycation end products and vascular structure and function},
  author={G. Soldatos and M. Cooper},
  journal={Current Hypertension Reports},
  year={2006},
  volume={8},
  pages={472-478}
}
Diabetes mellitus has now reached epidemic proportions in the Western world. The associated microvascular and macrovascular complications are a result of severe metabolic derangement, which leads to chronic tissue injury. Although there are a number of proposed pathophysiologic mechanisms for the vascular complications associated with diabetes, this review focuses predominantly on the role of advanced glycation end products (AGEs) in the pathogenesis of diabetes-associated atherosclerosis. The… Expand
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The present review summarizes the relevant evidence supporting the role of advanced glycation in promoting atherosclerosis and the epidemiologic studies demonstrating an association between AGEs and diabetic cardiovascular disease. Expand
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TLDR
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TLDR
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TLDR
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