Advanced glycation end products and neurodegenerative diseases: Mechanisms and perspective

@article{Li2012AdvancedGE,
  title={Advanced glycation end products and neurodegenerative diseases: Mechanisms and perspective},
  author={Jinlong Li and Danian Liu and Ling Sun and Yunting Lu and Zhongling Zhang Zhongling Zhang},
  journal={Journal of the Neurological Sciences},
  year={2012},
  volume={317},
  pages={1-5}
}
The age-related neurodegenerative disorders such as Alzheimer's, Parkinson's, and Huntington's diseases are characterized by the abnormal accumulation or aggregation of proteins. Advanced glycation end products (AGEs) are proteins or lipids that become glycated after exposure to sugars. The formation of AGEs promotes the deposition of proteins due to the protease resistant crosslinking between the peptides and proteins. Several proteins implicated in neurodegenerative diseases such as amyloid… CONTINUE READING
BETA
Tweets
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
SHOWING 1-10 OF 64 CITATIONS

FILTER CITATIONS BY YEAR

2013
2019

CITATION STATISTICS

  • 6 Highly Influenced Citations

  • Averaged 10 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 50 REFERENCES

Similar Papers

Loading similar papers…