Advanced glycation end products and antioxidant status in type 2 diabetic patients with and without peripheral artery disease.

@article{Lapolla2007AdvancedGE,
  title={Advanced glycation end products and antioxidant status in type 2 diabetic patients with and without peripheral artery disease.},
  author={Annunziata Lapolla and Francesco Piarulli and Giovanni Sartore and Antonio Ceriello and Eugenio Ragazzi and Rachele Reitano and Lorenzo Baccarin and Barbara Laverda and Domenico Fedele},
  journal={Diabetes care},
  year={2007},
  volume={30 3},
  pages={670-6}
}
OBJECTIVE Advanced glycation end products (AGEs), pentosidine and malondialdehyde (MDA), are elevated in type 2 diabetic subjects with coronary and carotid angiopathy. We investigated the relationship of AGEs, MDA, total reactive antioxidant potentials (TRAPs), and vitamin E in type 2 diabetic patients with and without peripheral artery disease (PAD). RESEARCH DESIGN AND METHODS AGEs, pentosidine, MDA, TRAP, vitamin E, and ankle-brachial index (ABI) were measured in 99 consecutive type 2… CONTINUE READING