Advanced gastrointestinal stromal tumor in Europe: a review of updated treatment recommendations

@article{Blay2009AdvancedGS,
  title={Advanced gastrointestinal stromal tumor in Europe: a review of updated treatment recommendations},
  author={Jean Yves Blay and Peter Reichardt},
  journal={Expert Review of Anticancer Therapy},
  year={2009},
  volume={9},
  pages={831 - 838}
}
The European Society for Medical Oncology (ESMO) recommendations on the management of gastrointestinal stromal tumor (GIST) have recently been updated. Imatinib 400 mg/day remains the standard first-line treatment for patients with metastatic GIST. Mutational analysis has received a strong recommendation for diagnostic purposes. Furthermore, patients with KIT exon 9-activating mutations are now recommended to receive imatinib 800 mg/day as first-line treatment. Following progression during… 

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