Advanced fabrication approaches to controlled delivery systems for epilepsy treatment

  title={Advanced fabrication approaches to controlled delivery systems for epilepsy treatment},
  author={Gilles Sebastiaan van Tienderen and Marius Berthel and Zhilian Yue and Mark J. Cook and Xiao Liu and Stephen Beirne and Gordon G. Wallace},
  journal={Expert Opinion on Drug Delivery},
  pages={915 - 925}
ABSTRACT Introduction: Epilepsy is a chronic brain disease characterized by unprovoked seizures, which can have severe consequences including loss of awareness and death. Currently, 30% of epileptic patients do not receive adequate seizure alleviation from oral routes of medication. Over the last decade, local drug delivery to the focal area of the brain where the seizure originates has emerged as a potential alternative and may be achieved through the fabrication of drug-loaded polymeric… 
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