Advanced analysis of biotin metabolites in body fluids allows a more accurate measurement of biotin bioavailability and metabolism in humans.

Abstract

In previous studies, the bioavailability of biotin in humans was estimated from the recovery of biotin in urine; urinary biotin was measured by microbial growth assays or assays of avidin-binding activity. These assays underestimate concentrations of biotin metabolites, which originate from beta-oxidation, sulfur oxidation or a combination. We have… (More)

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Cite this paper

@article{Zempleni1999AdvancedAO, title={Advanced analysis of biotin metabolites in body fluids allows a more accurate measurement of biotin bioavailability and metabolism in humans.}, author={Janos Zempleni and Donald M. Mock}, journal={The Journal of nutrition}, year={1999}, volume={129 2S Suppl}, pages={494S-497S} }