Amine-based CO2 separation is a leading technology expected to be available commercially within the next decade to enable post-combustion carbon capture for coal-fired power stations. Traditional CO2 capture process utilizing conventional amine solvents is very energy intensive and is also susceptible to solvent degradation by oxygen, SOx and NO2 in coal-fired flue gas, resulting in large operating cost. Hitachi addresses the above challenges of amine-based CCS for coal power with the following approach: 1) development of the latest advanced amine-based solvent that has longer service life and lower regeneration energy requirement than commercial solvents; 2) design integration of steam cycle and CO2 absorption desorption process; 3) total plant re-optimization involving the boiler, turbine, air quality control system, and CCS system. Hitachi started post-combustion CO2 capture R&D in the early 1990s, targeting coal-fired applications from the beginning. Our first pilot test program for coal-fired flue gas was carried out in cooperation with Tokyo Electric Power Corporation (TEPCO). The 1MWth slipstream facility at Yokosuka Power Station was operated for more than 3000 hours, including testing of MEA as benchmark and several commercial and proprietary advanced amine formulations. CO2 removal of 90% under various plant load conditions was demonstrated. A proprietary solvent blend has shown much lower regeneration energy (at 2800 kJ/kg CO2) than commercial MEA, as well as very low solvent loss. Hitachi is currently constructing a 5 MWth mobile pilot plant to be tested at several European power plants starting in 2010. This large pilot facility is designed to support further process integration and scaling-up for demonstration and commercial size plants. This paper will discuss solvent development, bench-scale and pilot testing, as well as system integration considerations of CO2 scrubbing process into large coal-fired power plants. INTRODUCTION In the United States about one half of the electricity is from coal. Worldwide coal contributes to over 40% of the electricity generation today and its share is expected to increase steadily over the coming decades. The continued dominance of coal in global energy structure and the growing concern of climate change necessitate accelerated development and deployment of new technologies for clean and efficient coal utilization. Coal-fired power plants with CO2 capture and sequestration (CCS) are widely expected to be an important part of a sensible future technology portfolio to achieve overall global CO2 reductions required for stabilizing atmospheric CO2 concentration and global warming.