Advance targeted transfusion in anemic cardiac surgical patients for kidney protection: an unblinded randomized pilot clinical trial.

@article{Karkouti2012AdvanceTT,
  title={Advance targeted transfusion in anemic cardiac surgical patients for kidney protection: an unblinded randomized pilot clinical trial.},
  author={Keyvan Karkouti and Duminda N Wijeysundera and Terrence M. Yau and Stuart A McCluskey and Christopher T. Chan and P Y H Wong and Mark Andrew Crowther and Siroos Hozhabri and William Scott Beattie},
  journal={Anesthesiology},
  year={2012},
  volume={116 3},
  pages={613-21}
}
INTRODUCTION : Acute kidney injury (AKI) is a serious complication of cardiac surgery, and preoperative anemia and perioperative erythrocyte transfusion are important risk factors. Prophylactic erythrocyte transfusion in anemic patients may, therefore, protect against AKI. METHODS : In this unblinded, parallel-group, randomized pilot trial, 60 anemic patients (hemoglobin 10-12 g/dL) undergoing cardiac surgery with cardiopulmonary bypass were randomized (1:1) to prophylactic transfusion (2… CONTINUE READING
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