Advance in the Rh blood group system.

  title={Advance in the Rh blood group system.},
  author={Eiji Kajii},
  journal={Nihon hoigaku zasshi = The Japanese journal of legal medicine},
  volume={52 1},
  • Eiji Kajii
  • Published 1998 in
    Nihon hoigaku zasshi = The Japanese journal of…
The Rh blood group antigens are associated with non-glycosylated red blood cell membrane proteins encoded by two closely related genes, RHD and RHCE. Both RH genes have 10 exons and the open reading frames of their transcripts are composed of 1251 nucleotides. The sequence analyses of RHCE transcripts revealed that RhC/c and RhE/e are related to six nucleotide substitutions and a single substitution, respectively. Molecular analyses have elucidated the genetic background of various RhD and RhCE… CONTINUE READING


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