Adult zebrafish model of bacterial meningitis in Streptococcus agalactiae infection.

  title={Adult zebrafish model of bacterial meningitis in Streptococcus agalactiae infection.},
  author={Hayley Patterson and Anni K. Saralahti and Mataleena Parikka and Shaynoor Dramsi and Patrick Trieu-Cuot and Claire Poyart and Samuli Rounioja and Mika R{\"a}met},
  journal={Developmental and comparative immunology},
  volume={38 3},
Streptococcus agalactiae (Group B Streptococcus, GBS) is the major cause of severe bacterial disease and meningitis in newborns. The zebrafish (Danio rerio) has recently emerged as a valuable and powerful vertebrate model for the study of human streptococcal infections. In the present study we demonstrate that adult zebrafish are susceptible to GBS infection through the intraperitoneal and intramuscular routes of infection. Following intraperitoneal challenge with GBS, zebrafish developed a… CONTINUE READING


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