Adult thymectomy results in loss of T-dependent mitogen response in mouse spleen cells

@article{Jacobs1975AdultTR,
  title={Adult thymectomy results in loss of T-dependent mitogen response in mouse spleen cells},
  author={Diane M. Jacobs and William Byrd},
  journal={Nature},
  year={1975},
  volume={255},
  pages={153-155}
}
THERE is overwhelming evidence that murine thymocytes represent a heterogeneous population of cells that can be divided into discrete subpopulations on the basis of surface antigen markers1,2, drug sensitivity3, physical characteristics4,5 and responsiveness to mitogens6. There is some indication that a similar heterogeneity with regard to biological function exists within the peripheral thymus-derived (T) lymphocyte population (reviewed in refs 7–9). Several investigators have shown that… CONTINUE READING

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