Adult testicular enlargement induced by neonatal hypothyroidism is accompanied by increased Sertoli and germ cell numbers.

@article{Hess1993AdultTE,
  title={Adult testicular enlargement induced by neonatal hypothyroidism is accompanied by increased Sertoli and germ cell numbers.},
  author={Rex Allen Hess and Paul S. Cooke and David Bunick and John D. Kirby},
  journal={Endocrinology},
  year={1993},
  volume={132 6},
  pages={2607-13}
}
Our previous studies have shown that transient neonatal hypothyroidism, induced by treatment with the reversible goitrogen 6-propyl-2-thiouracil (PTU), increases testicular size and daily sperm production in the adult rat by up to 82% and 136%, respectively. The objective of the present study was to examine morphological and functional changes in adult seminiferous tubules associated with PTU-induced increases in testicular size and sperm production. Sprague-Dawley rats were treated with PTU… CONTINUE READING

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