Adult-onset subacute sclerosing panencephalitis presenting as a degenerative dementia syndrome

@article{Frings2002AdultonsetSS,
  title={Adult-onset subacute sclerosing panencephalitis presenting as a degenerative dementia syndrome},
  author={Markus Frings and Ingo Blaeser and Oliver Kastrup},
  journal={Journal of Neurology},
  year={2002},
  volume={249},
  pages={942-943}
}
Sirs: Subacute sclerosing panencephalitis (SSPE) is a chronic reactivated infection with measles virus causing progressive inflammation and gliosis of the brain, mostly in children with an average age of onset of 14 years. The clinical course initially is marked by changes in behaviour, followed by myoclonic jerks, seizures and motor abnormalities, accompanied by progressive dementia. Later in the course pyramidal signs, stupor and finally decorticate postures and coma ensue. The course is… CONTINUE READING

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