Adult onset haemophagocytic lymphohistiocytosis prognosis is affected by underlying disease: analysis of a single-institution series of 174 patients.

@article{Zhang2018AdultOH,
  title={Adult onset haemophagocytic lymphohistiocytosis prognosis is affected by underlying disease: analysis of a single-institution series of 174 patients.},
  author={Qiaolei Zhang and Li Li and Lixia Zhu and Jingjing Zhu and Xiudi Yang and De Qun Zhou and Yanglong Zheng and Mingyu Zhu and Mixue Xie and Jianai Sun and Xueying Li and Ying Wu and Zhangyue Wei and Wanzhuo Xie and Xiujin Ye},
  journal={Swiss medical weekly},
  year={2018},
  volume={148},
  pages={
          w14641
        }
}
BACKGROUND Haemophagocytic lymphohistiocytosis (HLH) is a rare clinical syndrome characterised by activation of the mononuclear phagocytic system, and often leads to progressive multiple organ failure. The diagnosis of HLH is made late by most physicians. METHODS To confirm the diagnosis of acquired HLH made in a single-institution series of adult patients with HLH-04 criteria, we applied the HScore and evaluated prognostic factors associated with clinical outcome. RESULTS A total of 174… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 28 REFERENCES

Hemophago - cytic lymphohistiocytosis : clinical analysis of 103 adult patients

  • F Li, P Li, +3 authors X Huang
  • Medi - cine ( Baltimore ) .
  • 2014