Adult-onset autoimmune diabetes: current knowledge and implications for management

@article{Buzzetti2017AdultonsetAD,
  title={Adult-onset autoimmune diabetes: current knowledge and implications for management},
  author={Raffaella Buzzetti and Simona Zampetti and Ernesto Maddaloni},
  journal={Nature Reviews Endocrinology},
  year={2017},
  volume={13},
  pages={674-686}
}
Adult-onset autoimmune diabetes is a heterogeneous disease that is characterized by a reduced genetic load, a less intensive autoimmune process and a mild metabolic decompensation at onset compared with young-onset type 1 diabetes mellitus (T1DM). The majority of patients with adult-onset autoimmune diabetes do not require insulin treatment for at least 6 months after diagnosis. Such patients are defined as having latent autoimmune diabetes in adults (LADA), which is distinct from classic adult… 

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