Adult olfactory ensheathing glia promote the long-distance growth of adult retinal ganglion cell neurites in vitro.

@article{Leaver2006AdultOE,
  title={Adult olfactory ensheathing glia promote the long-distance growth of adult retinal ganglion cell neurites in vitro.},
  author={Simone G. Leaver and Alan R Harvey and Giles W. Plant},
  journal={Glia},
  year={2006},
  volume={53 5},
  pages={467-76}
}
In vivo, transplanted adult olfactory ensheathing glia (OEG) and adult Schwann cells (SC) can support the regrowth of at least some transected axons within adult CNS neuropil. In the present study, we developed an in vitro adult rat retinal explant model to explore the influence of primary adult SC and OEG on retinal ganglion cell (RGC) neurite regrowth in the presence of glial cells endogenous to the retina. Retinal quadrants were plated RGC-side down onto aclar hats coated with either pure… CONTINUE READING

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