Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus

  title={Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus},
  author={Heather A. Cameron and Ronald D. G. McKay},
  journal={Journal of Comparative Neurology},
Knowing the rate of addition of new granule cells to the adult dentate gyrus is critical to understanding the function of adult neurogenesis. [] Key Result Within 5-12 days of BrdU injection, a substantial pool of immature granule neurons, 50% of all BrdU-labeled cells in the dentate gyrus, could be identified with neuron-specific antibodies TuJ1 and TUC-4. This number of new granule neurons generated each month is 6% of the total size of the granule cell population and 30-60% of the size of the afferent and…

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