Adult neurogenesis and functional plasticity in neuronal circuits

@article{Lledo2006AdultNA,
  title={Adult neurogenesis and functional plasticity in neuronal circuits},
  author={Pierre-Marie Lledo and Mariana Mac{\'i}as Alonso and Matthew S. Grubb},
  journal={Nature Reviews Neuroscience},
  year={2006},
  volume={7},
  pages={179-193}
}
The adult brain is a plastic place. To ensure that the mature nervous system's control of behaviour is flexible in the face of a varying environment, morphological and physiological changes are possible at many levels, including that of the entire cell. In two areas of the adult brain — the olfactory bulb and the dentate gyrus — new neurons are generated throughout life and form an integral part of the normal functional circuitry. This process is not fixed, but highly modulated, revealing a… 

Adult neurogenesis and modulation of neural circuit function

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Functions and dysfunctions of adult hippocampal neurogenesis.

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Questions about adult neurogenesis, an adaptive response to challenges imposed by an environment and/or internal state of the animal, and how this functional demand is translated into signals a precursor cell can detect are addressed.
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