Adult microbiota‐deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus

@inproceedings{Luczynski2016AdultMM,
  title={Adult microbiota‐deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus},
  author={Pauline Luczynski and Se{\'a}n O. Whelan and Colette O'Sullivan and Gerard Clarke and Fergus Shanahan and Timothy G Dinan and John F Cryan},
  booktitle={The European journal of neuroscience},
  year={2016}
}
Increasing evidence implicates the microbiota in the regulation of brain and behaviour. Germ-free mice (GF; microbiota deficient from birth) exhibit altered stress hormone signalling and anxiety-like behaviours as well as deficits in social cognition. Although the mechanisms underlying the ability of the gut microbiota to influence stress responsivity and behaviour remain unknown, many lines of evidence point to the amygdala and hippocampus as likely targets. Thus, the aim of this study was to… CONTINUE READING
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