Adult mice generated from induced pluripotent stem cells

@article{Boland2009AdultMG,
  title={Adult mice generated from induced pluripotent stem cells},
  author={Michael J. Boland and Jennifer L. Hazen and K. Nazor and Alberto R Rodriguez and Wesley D. Gifford and Greg Martin and S. Kupriyanov and K. Baldwin},
  journal={Nature},
  year={2009},
  volume={461},
  pages={91-94}
}
Recent landmark experiments have shown that transient overexpression of a small number of transcription factors can reprogram differentiated cells into induced pluripotent stem (iPS) cells that resemble embryonic stem (ES) cells. These iPS cells hold great promise for medicine because they have the potential to generate patient-specific cell types for cell replacement therapy and produce in vitro models of disease, without requiring embryonic tissues or oocytes. Although current iPS cell lines… Expand
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Complete reprogramming to all-iPS mice
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