Adult human dental pulp stem cells differentiate toward functionally active neurons under appropriate environmental cues.

@article{Arthur2008AdultHD,
  title={Adult human dental pulp stem cells differentiate toward functionally active neurons under appropriate environmental cues.},
  author={Agnes Arthur and G Y Rychkov and Songtao Shi and Simon Andrea Koblar and Stan Gronthos},
  journal={Stem cells},
  year={2008},
  volume={26 7},
  pages={1787-95}
}
Human adult dental pulp stem cells (DPSCs) reside within the perivascular niche of dental pulp and are thought to originate from migrating cranial neural crest (CNC) cells. During embryonic development, CNC cells differentiate into a wide variety of cell types, including neurons of the peripheral nervous system. Previously, we have demonstrated that DPSCs derived from adult human third molar teeth differentiate into cell types reminiscent of CNC embryonic ontology. We hypothesized that DPSCs… CONTINUE READING
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Human Dental Pulp Stem Cells: Characterization and Developmental Potential

  • S Gronthos, N Cherman, PG Robey
  • Totowa, NJ: Humana Press Inc.,
  • 2004

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