Adult human RPE can be activated into a multipotent stem cell that produces mesenchymal derivatives.


The retinal pigment epithelium (RPE) is a monolayer of cells underlying and supporting the neural retina. It begins as a plastic tissue, capable, in some species, of generating lens and retina, but differentiates early in development and remains normally nonproliferative throughout life. Here we show that a subpopulation of adult human RPE cells can be… (More)
DOI: 10.1016/j.stem.2011.11.018


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