Adult glioblastoma multiforme survival in the temozolomide era: a population-based analysis of Surveillance, Epidemiology, and End Results registries.

@article{Darefsky2012AdultGM,
  title={Adult glioblastoma multiforme survival in the temozolomide era: a population-based analysis of Surveillance, Epidemiology, and End Results registries.},
  author={Amy S. Darefsky and Joseph Taylor King and Robert S. Dubrow},
  journal={Cancer},
  year={2012},
  volume={118 8},
  pages={
          2163-72
        }
}
BACKGROUND Survival after a glioblastoma multiforme (GBM) diagnosis remained static during the several decades before 1999. We hypothesized that the progressive increase in temozolomide use for GBM treatment that began in 1999 in the United States would be paralleled by a corresponding improvement in survival. METHODS We included 19,674 GBM cases, ages 20 years or greater, diagnosed 1993 to 2007 in the population-based Surveillance, Epidemiology, and End Results Program database. We used… CONTINUE READING
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