Adult generation of glutamatergic olfactory bulb interneurons

  title={Adult generation of glutamatergic olfactory bulb interneurons},
  author={Monika S. Brill and Jovica Ninkovic and Eleanor M Winpenny and Rebecca D. Hodge and Ilknur Ozen and Roderick Yang and Alexandra Lepier and Sergio Gasc{\'o}n and Ferenc Erd{\'e}lyi and G{\'a}bor Szab{\'o} and Carlos M. Parras and François Guillemot and Michael Frotscher and Benedikt Berninger and Robert F Hevner and Olivier Raineteau and Magdalena G{\"o}tz},
  booktitle={Nature Neuroscience},
The adult mouse subependymal zone (SEZ) harbors neural stem cells that are thought to exclusively generate GABAergic interneurons of the olfactory bulb. We examined the adult generation of glutamatergic juxtaglomerular neurons, which had dendritic arborizations that projected into adjacent glomeruli, identifying them as short-axon cells. Fate mapping revealed that these originate from Neurog2- and Tbr2-expressing progenitors located in the dorsal region of the SEZ. Examination of the… CONTINUE READING
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