Adult fragile X syndrome

@article{Rudelli2004AdultFX,
  title={Adult fragile X syndrome},
  author={Raoul D Rudelli and William Ted Brown and Karol Wiśniewski and Edmund C Jenkins and Milena Laure-Kamionowska and Fiona Connell and Henryk M. Wiśniewski},
  journal={Acta Neuropathologica},
  year={2004},
  volume={67},
  pages={289-295}
}
Fragile X syndrome [fra (X)] is currently accepted as the second most frequent chromosomal disorder associated with developmental disability. Although next to Down syndrome in frequency, no postmortem studies of confirmed adult cases had been reported. The autopsy examination of a 62-year-old, moderately retarded man with the fra (X) syndrome confirmed the preferential involvement of cerebral and testicular structures in this disorder.Dendritic spine abnormalities of the type observed in… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 46 extracted citations

Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2013
View 9 Excerpts
Highly Influenced

Fragile X syndrome: an aging perspective.

Developmental disabilities research reviews • 2013
View 4 Excerpts
Highly Influenced

Brain-derived neurotrophic factor rescues synaptic plasticity in a mouse model of fragile X syndrome.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2007
View 6 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 55 references

Neurobiology of Down's syndrome

Progress in Neurobiology • 1983
View 1 Excerpt

Autism is associated with the fragile-X syndrome.

Journal of autism and developmental disorders • 1982
View 1 Excerpt

Similar Papers

Loading similar papers…