Adult fragile X syndrome

  title={Adult fragile X syndrome},
  author={Raoul D Rudelli and William Ted Brown and Karol Wiśniewski and Edmund C Jenkins and Milena Laure-Kamionowska and Fiona Connell and Henryk M. Wiśniewski},
  journal={Acta Neuropathologica},
Fragile X syndrome [fra (X)] is currently accepted as the second most frequent chromosomal disorder associated with developmental disability. Although next to Down syndrome in frequency, no postmortem studies of confirmed adult cases had been reported. The autopsy examination of a 62-year-old, moderately retarded man with the fra (X) syndrome confirmed the preferential involvement of cerebral and testicular structures in this disorder.Dendritic spine abnormalities of the type observed in… CONTINUE READING


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