Adult equine bone marrow stromal cells produce a cartilage-like ECM mechanically superior to animal-matched adult chondrocytes.

@article{Kopesky2010AdultEB,
  title={Adult equine bone marrow stromal cells produce a cartilage-like ECM mechanically superior to animal-matched adult chondrocytes.},
  author={Paul W. Kopesky and H-Y Lee and Eric J. Vanderploeg and John David Kisiday and David D. Frisbie and Anna Plaas and C. Jimenez Ortiz and Alan J. Grodzinsky},
  journal={Matrix biology : journal of the International Society for Matrix Biology},
  year={2010},
  volume={29 5},
  pages={427-38}
}
Our objective was to evaluate the age-dependent mechanical phenotype of bone marrow stromal cell- (BMSC-) and chondrocyte-produced cartilage-like neo-tissue and to elucidate the matrix-associated mechanisms which generate this phenotype. Cells from both immature (2-4 month-old foals) and skeletally-mature (2-5 year-old adults) mixed-breed horses were isolated from animal-matched bone marrow and cartilage tissue, encapsulated in self-assembling-peptide hydrogels, and cultured with and without… CONTINUE READING
31 Citations
54 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 31 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 54 references

Similar Papers

Loading similar papers…