Adult T-cell leukemia/lymphoma development in HTLV-1-infected humanized SCID mice.

Abstract

The molecular and genetic factors induced by human T-lymphotropic virus type-1 (HTLV-1) that initiate adult T-cell leukemia/lymphoma (ATLL) remain unclear, in part from the lack of an animal model that accurately recapitulates leukemogenesis. HTLV-1-infected humanized nonobese diabetic severe combined immunodeficiency (HU-NOD/SCID) mice were generated by… (More)
DOI: 10.1182/blood-2009-10-246959

Topics

8 Figures and Tables

Cite this paper

@article{Banerjee2010AdultTL, title={Adult T-cell leukemia/lymphoma development in HTLV-1-infected humanized SCID mice.}, author={Prabal Banerjee and A P P Tripp and Michael D. Lairmore and Lindsey B. Crawford and Michelle A Sieburg and Juan Carlos Pena Ramos and William J. Harrington and Mark A. Beilke and Gerold Feuer}, journal={Blood}, year={2010}, volume={115 13}, pages={2640-8} }