Adult Human Brain Neural Progenitor Cells (NPCs) and Fibroblast-Like Cells Have Similar Properties In Vitro but Only NPCs Differentiate into Neurons

@inproceedings{Park2012AdultHB,
  title={Adult Human Brain Neural Progenitor Cells (NPCs) and Fibroblast-Like Cells Have Similar Properties In Vitro but Only NPCs Differentiate into Neurons},
  author={Thomas H. Park and Hector J. Monzo and Edward William Mee and Peter S. Bergin and Hoon Heng Teoh and Johanna M Montgomery and Richard L. M. Faull and Maurice A Curtis and Mike Dragunow},
  booktitle={PloS one},
  year={2012}
}
The ability to culture neural progenitor cells from the adult human brain has provided an exciting opportunity to develop and test potential therapies on adult human brain cells. To achieve a reliable and reproducible adult human neural progenitor cell (AhNPC) culture system for this purpose, this study fully characterized the cellular composition of the AhNPC cultures, as well as the possible changes to this in vitro system over prolonged culture periods. We isolated cells from the neurogenic… CONTINUE READING
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