Aducanumab and Its Effects on Tau Pathology: Is This the Turning Point of Amyloid Hypothesis?

@article{Silvestro2022AducanumabAI,
  title={Aducanumab and Its Effects on Tau Pathology: Is This the Turning Point of Amyloid Hypothesis?},
  author={Serena Silvestro and Andrea Valeri and Emanuela Mazzon},
  journal={International Journal of Molecular Sciences},
  year={2022},
  volume={23}
}
Alzheimer’s disease (AD) is a neurodegenerative disorder affecting millions of people around the world. The two main pathological mechanisms underlying the disease are beta-amyloid (Aβ) plaques and intracellular neurofibrillary tangles (NFTs) of Tau proteins in the brain. Their reduction has been associated with slowing of cognitive decline and disease progression. Several antibodies aimed to target Aβ or Tau in order to represent hope for millions of patients, but only a small number managed… 

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