Adsorption of oral antidotes for acetaminophen poisoning (methionine and n-acetylcysteine) by activated charcoal.

@article{KleinSchwartz1981AdsorptionOO,
  title={Adsorption of oral antidotes for acetaminophen poisoning (methionine and n-acetylcysteine) by activated charcoal.},
  author={Wendy Klein-Schwartz and Gary M. Oderda},
  journal={Clinical toxicology},
  year={1981},
  volume={18 3},
  pages={
          283-90
        }
}
  • Wendy Klein-Schwartz, Gary M. Oderda
  • Published 1981
  • Medicine
  • Clinical toxicology
  • An in vitro experiment was performed to assess the degree of adsorption of oral antidotes for acetaminophen poisoning, methionine and N-acetylcysteine, by activated charcoal. Results indicate that activated charcoal effectively adsorbs both methionine and N-acetylcysteine. Since these agents must be absorbed from the GI tract to prevent acetaminophen hepatotoxicity, concurrent administration of methionine or N-acetylcysteine and activated charcoal would be expected to markedly diminish their… CONTINUE READING