Adrm1, a putative cell adhesion regulating protein, is a novel proteasome-associated factor.

@article{Jrgensen2006Adrm1AP,
  title={Adrm1, a putative cell adhesion regulating protein, is a novel proteasome-associated factor.},
  author={Jakob Ploug J\orgensen and Anne-Marie B. Lauridsen and Poul Kristensen and Karen Dissing and Anders Johnsen and Klavs B. Hendil and Rasmus Hartmann-Petersen},
  journal={Journal of molecular biology},
  year={2006},
  volume={360 5},
  pages={1043-52}
}
We have identified Adrm1 as a novel component of the regulatory ATPase complex of the 26 S proteasome: Adrm1 was precipitated with an antibody to proteasomes and vice versa. Adrm1 co-migrated with proteasomes on gel-filtration chromatography and non-denaturing polyacrylamide gel electrophoresis. Adrm1 has been described as an interferon-gamma-inducible, heavily glycosylated membrane protein of 110 kDa. However, we found Adrm1 in mouse tissues only as a 42 kDa peptide, corresponding to the mass… CONTINUE READING

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