• Medicine
• Published in Toxicology letters 1983
• DOI:10.1016/0378-4274(83)90109-1

Adriamycin causes hyperlipemia as a consequence of nephrotoxicity.

@article{Bizzi1983AdriamycinCH,
  title={Adriamycin causes hyperlipemia as a consequence of nephrotoxicity.},
  author={Alberto Bizzi and Luca Ceriani and M Gerundino and Annamaria Spina and Maria Teresa Tacconi and E. Veneroni},
  journal={Toxicology letters},
  year={1983},
  volume={18 3},
  pages={
          291-300
        }
}

• Alberto Bizzi, Luca Ceriani, +3 authors E. Veneroni

Adriamycin induced hyperlipemia: its features and mechanism(s) in rats were investigated. Massive hyperlipemia occurred 14-21 days after a single dose of adriamycin (7.5 mg/kg i.v.). All lipoprotein fractions were affected. Mild but significant changes in tissues were observed (liver and intestine triglycerides and kidney phospholipids were reduced). Lipid synthesis and secretion was decreased, as shown by the Triton WR1339 test 7 days after treatment, but subsequently returned to normal… CONTINUE READING

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