Adriamycin, 14‐hydroxydaimomycin, a new antitumor antibiotic from S. Peucetius var. caesius

@article{Arcamone1969Adriamycin1A,
  title={Adriamycin, 14‐hydroxydaimomycin, a new antitumor antibiotic from S. Peucetius var. caesius},
  author={Federico Arcamone and Giuseppe Cassinelli and G Fantini and Arpad Grein and Piergiuseppe Orezzi and Chaitrali Satish Pol and Celestino Spalla},
  journal={Biotechnology and Bioengineering},
  year={1969},
  volume={11}
}
Streptomyces peucetius var. caesius, obtained from S. peucetius, the daunomycin producing microorganism, by mutagenic treatment, differs from the parent culture by the color of the vegetative and aerial mycelia and by its antibiotic, producing ability. S. peucetius var. caesius accumulates adriamycin in submerged and aerated culture on a medium containing glucose, brewer's yeast, and inorganic, salts both in shake flasks and in stirred fementers. Isolation of the product is performed by solvent… 
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  • A. Grein
  • Biology
    Advances in applied microbiology
  • 1987
Biologically active secondary metabolites from Actinomycetes
TLDR
The diversity of secondary metabolites produced by actinomycete strains with respect to their chemical structure, biological activity and origin is demonstrated and it is concluded that the discovery of new bioactive compounds will continue to pose a great challenge for scientists.
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