Adrenomedullin facilitates reinnervation of phenol-injured perivascular nerves in the rat mesenteric resistance artery.

@article{Hobara2007AdrenomedullinFR,
  title={Adrenomedullin facilitates reinnervation of phenol-injured perivascular nerves in the rat mesenteric resistance artery.},
  author={Narumi Hobara and Mitsuhiro Goda and Yoshitaka Kitamura and Toshiaki Sendou and Yutaka Gomita and Hiromu Kawasaki},
  journal={Neuroscience},
  year={2007},
  volume={144 2},
  pages={721-30}
}
Our previous report showed that innervation of calcitonin gene-related peptide (CGRP)- and neuropeptide Y (NPY)-containing nerves in rat mesenteric resistance arteries was markedly reduced by topical application of phenol, and that nerve growth factor (NGF) facilitates the reinnervation of both nerves. We also demonstrated that a CGRP superfamily peptide, adrenomedullin, is distributed in perivascular nerves of rat mesenteric resistance arteries. In the present study, we investigated the… CONTINUE READING