Adrenocorticotropin induces calcium oscillations in adrenal fasciculata cells: single cell imaging.

@article{Kimoto1996AdrenocorticotropinIC,
  title={Adrenocorticotropin induces calcium oscillations in adrenal fasciculata cells: single cell imaging.},
  author={Tetsuya Kimoto and Youichi Ohta and S Kawato},
  journal={Biochemical and biophysical research communications},
  year={1996},
  volume={221 1},
  pages={
          25-30
        }
}
With fluorescence microscopic imaging, we have demonstrated that the Ca2+ signaling occurred in individual Calcium Green-1 loaded bovine adrenal fasciculata cells upon stimulation with adrenocorticotropin (ACTH) at physiological concentration of 0.1-100 pM. We observed three patterns of Ca2+ signaling which were Ca2+ oscillations (33%), step-like increase in Ca2+ concentration (10%), and Ca2+ oscillations superimposed on step-like increase in Ca2+ (57%). The oscillation in intracellular Ca2… CONTINUE READING

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