Adrenocorticotropin hyperresponse to the corticotropin-releasing hormone-mediated stimulus of naloxone in patients with myotonic dystrophy.

Abstract

We previously showed that CRH-mediated stimuli, including exogenous CRH, cause ACTH hypersecretion in many myotonic dystrophy (DM) patients. We confirmed this by giving naloxone, a stimulator of endogenous CRH release, to a large number of DM patients and controls. DM patients, first degree relatives, and normal controls received i.v. naloxone at 1400 h… (More)

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@article{Grice1995AdrenocorticotropinHT, title={Adrenocorticotropin hyperresponse to the corticotropin-releasing hormone-mediated stimulus of naloxone in patients with myotonic dystrophy.}, author={Jeffrey E. Grice and R V Jackson and Gregory I Hockings and David James Torpy and Megan Walters and Georgina V Crosbie}, journal={The Journal of clinical endocrinology and metabolism}, year={1995}, volume={80 1}, pages={179-84} }