Adrenocorticotrophin and luteinizing hormone responses to N-methyl-D-aspartate during fetal development in sheep.

@article{Brooks1996AdrenocorticotrophinAL,
  title={Adrenocorticotrophin and luteinizing hormone responses to N-methyl-D-aspartate during fetal development in sheep.},
  author={Ashley N Brooks and David C. Howe},
  journal={Journal of neuroendocrinology},
  year={1996},
  volume={8 4},
  pages={
          315-21
        }
}
The hypothalamic mechanisms which underlie the development of the fetal neuroendocrine system are unclear. However, in adult animals neuroactive amino-acids, particularly those acting at the N-methyl-D-aspartate (NMDA) receptor, have been shown to be important transmitters involved in the neuroendocrine regulation of the anterior pituitary gland. In this study we have investigated the potential role of NMDA in the neuroendocrine regulation of fetal pituitary function, by examining the ontogeny… CONTINUE READING
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