Adrenocortical tumor in a patient with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.

@article{Pang1981AdrenocorticalTI,
  title={Adrenocortical tumor in a patient with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.},
  author={Stella W. Pang and Dirk De Becker and James D. Cotelingam and Thomas P. Foley and Allan L. Drash},
  journal={Pediatrics},
  year={1981},
  volume={68 2},
  pages={
          242-6
        }
}
An adrenal cortical tissue tumor developed in a patient with poorly controlled salt-losing congenital adrenal hyperplasia. A 16-year-old girl became progressively virilized from 13 to 16 years of age. Base line serum progesterone, 17-hydroxyprogesterone, and testosterone levels were high and there was a diurnal pattern of the hormones. Initially elevated urinary 17-ketosteroid and serum steroid levels were decreased by high dose dexamethasone therapy, and at laparotomy an adenoma was found in… CONTINUE READING

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