Adrenocortical effects of oral estrogens and soy isoflavones in female monkeys.

@article{Wood2004AdrenocorticalEO,
  title={Adrenocortical effects of oral estrogens and soy isoflavones in female monkeys.},
  author={Charles E Wood and J. Mark Cline and Mary S Anthony and Thomas C. Register and Jay R. Kaplan},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2004},
  volume={89 5},
  pages={
          2319-25
        }
}
The goal of this study was to evaluate the long-term adrenocortical effects of premenopausal oral contraceptives (OC) and postmenopausal conjugated equine estrogens (CEE) and soy isoflavones in a female cynomolgus monkey model. Half of the animals received a triphasic OC for a period of 26 months, after which all monkeys were ovariectomized and randomized to one of three diet groups for 36 months: 1). isoflavone-depleted soy protein (control) (n = 54); 2). soy protein with isoflavones (129 mg/d… Expand
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TLDR
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