Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study.

  title={Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study.},
  author={Eric J Brunner and Harry Hemingway and Brian R. Walker and Michael Page and Philip B Clarke and Monica Juneja and Martin J. Shipley and Meena Kumari and Ruth Andrew and Jonathan R Seckl and Andrew Papadopoulos and Stuart A. Checkley and Ann Rumley and Gordon D. O. Lowe and Stephen A Stansfeld and Michael Marmot},
  volume={106 21},
BACKGROUND The causes of metabolic syndrome (MS), which may be a precursor of coronary disease, are uncertain. We hypothesize that disturbances in neuroendocrine and cardiac autonomic activity (CAA) contribute to development of MS. We examine reversibility and the power of psychosocial and behavioral factors to explain the neuroendocrine adaptations that accompany MS. METHODS AND RESULTS This was a double-blind case-control study of working men aged 45 to 63 years drawn from the Whitehall II… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 188 extracted citations

Caregiving, Metabolic Syndrome Indicators, and 1-year Decline in Walking Speed: Results of Caregiver-SOF

The journals of gerontology. Series A, Biological sciences and medical sciences • 2010
View 5 Excerpts
Highly Influenced

Health problems and stress in Information Technology and Business Process Outsourcing employees

Journal of pharmacy & bioallied sciences • 2015
View 4 Excerpts
Highly Influenced

The physical activity, stress and metabolic syndrome triangle: a guide to unfamiliar territory for the obesity researcher.

Obesity reviews : an official journal of the International Association for the Study of Obesity • 2010
View 6 Excerpts
Highly Influenced


Publications referenced by this paper.
Showing 1-10 of 32 references

Inequalities in health.

The New England journal of medicine • 2001
View 1 Excerpt

Similar Papers

Loading similar papers…