Corpus ID: 2974088

Adrenergic receptors and sympathetic agents in isolated human pulmonary arteries.

  title={Adrenergic receptors and sympathetic agents in isolated human pulmonary arteries.},
  author={J. Boe and B. Simonsson},
  journal={European journal of respiratory diseases},
  volume={61 4},
  • J. Boe, B. Simonsson
  • Published 1980
  • Medicine
  • European journal of respiratory diseases
  • We tested the in vitro contractility of 88 segmental pulmonary arteries from 46 patients undergoing thoracic surgery. The vascular strips, taken from macroscopically healthy lung tissue, were devoid of spontaneous adrenergic tone. Cumulative dose-response curves with epinephrine and norepinephrine showed graded contraction. There was no significant difference between the two substances concerning mean maximal tension, threshold doses, ED50 or concentrations causing maximal contraction. Alpha… CONTINUE READING
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