Adrenergic receptor-mediated activation of FGF-21-adiponectin axis exerts atheroprotective effects in brown adipose tissue-transplanted apoE-/- mice.

@article{Kikai2018AdrenergicRA,
  title={Adrenergic receptor-mediated activation of FGF-21-adiponectin axis exerts atheroprotective effects in brown adipose tissue-transplanted apoE-/- mice.},
  author={Masakazu Kikai and Hiroyuki Yamada and Noriyuki Wakana and Kensuke Terada and Keita Yamamoto and Naotoshi Wada and Shinichiro Motoyama and Makoto Saburi and Takeshi Sugimoto and Daisuke Irie and Taku Kato and Hiroyuki Kawahito and Takehiro Ogata and Satoaki Matoba},
  journal={Biochemical and biophysical research communications},
  year={2018},
  volume={497 4},
  pages={1097-1103}
}
Brown adipose tissue (BAT) has been found as an endocrine organ that maintains metabolic homeostasis; however, the effects on atherosclerosis remain undefined. Here, we investigated the effect of experimental BAT transplantation on atherosclerosis. Interscapular BAT was dissected from wild-type mice and transplanted into the visceral cavity of 12-week-old… CONTINUE READING