Adrenergic gating of Hebbian spike-timing-dependent plasticity in cortical interneurons.

Abstract

In pyramidal cells, the induction of spike-dependent plasticity (STDP) follows a simple Hebbian rule in which the order of presynaptic and postsynaptic firing dictates the induction of LTP or LTD. In contrast, cortical fast spiking (FS) interneurons, which control the rate and timing of pyramidal cell firing, reportedly express timing-dependent LTD, but not… (More)
DOI: 10.1523/JNEUROSCI.5741-12.2013

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