Adrenergic coronary vasoconstriction during myocardial underperfusion.

  title={Adrenergic coronary vasoconstriction during myocardial underperfusion.},
  author={Eric O. Feigl and Charles W. Buffington and Howard J. Nathan},
  volume={75 1 Pt 2},
The effects of adrenergic alpha-receptor-mediated coronary vasoconstriction were examined in the presence of coronary stenosis and during experimental coronary hypoperfusion. Adrenergic coronary vasoconstriction was observed to operate even in the presence of coronary stenosis to limit oxygen delivery to the heart and increase myocardial oxygen extraction, but this vasoconstrictor effect did not result in myocardial lactate production. During constant coronary pressure perfusion the transmural… CONTINUE READING

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