Adrenergic Modulation of Potassium Currents in Isolated Human Atrial Myocytes.

@article{Su1994AdrenergicMO,
  title={Adrenergic Modulation of Potassium Currents in Isolated Human Atrial Myocytes.},
  author={M. Jai Su and J F Chi and S Chu},
  journal={Journal of biomedical science},
  year={1994},
  volume={1 3},
  pages={193-200}
}
The adrenergic modulation of inwardly rectifying and depolarization-activated outward potassium currents was studied in single cardiac myocytes obtained from the human atrium. Membrane currents were recorded in enzymatically dissociated cells using the whole-cell voltage-clamp technique. It was observed that, in the presence or absence of atenolol (or 1 &mgr;M propranolol), 30 &mgr;M phenylephrine attenuated inwardly rectifying and depolarization-activated outward potassium currents including… CONTINUE READING