Adrenergic α2A receptor gene is not associated with methylphenidate response in adults with ADHD

@article{Contini2010AdrenergicR,
  title={Adrenergic α2A receptor gene is not associated with methylphenidate response in adults with ADHD},
  author={Ver{\^o}nica Contini and Marcelo Moraes Victor and Caio C. S. Cerqueira and Evelise Regina Polina and Eugenio Horacio Grevet and Carlos Alberto Iglesias Salgado and Rafael Gomes Karam and Eduardo Schneider Vitola and Paulo da Silva Belmonte-de-Abreu and Claiton Henrique Dotto Bau},
  journal={European Archives of Psychiatry and Clinical Neuroscience},
  year={2010},
  volume={261},
  pages={205-211}
}
Adrenergic α2A receptor gene (ADRA2A) is one of the most promising candidate genes for ADHD pharmacogenetics. Thus far, three studies have investigated the association between the ADRA2A −1291 C>G polymorphism and the therapeutic response to methylphenidate (MPH) in children with ADHD, all of them with positive results. The aim of this study is to investigate, for the first time, the association between three ADRA2A polymorphisms (−1291 C>G, −262 G>A, and 1780 C>T) and the response to MPH in… CONTINUE READING
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