Adrenergic, respiratory, and cardiovascular effects of core cooling in humans.

@article{Frank1997AdrenergicRA,
  title={Adrenergic, respiratory, and cardiovascular effects of core cooling in humans.},
  author={S M Frank and Michael S. Higgins and Lee A. Fleisher and James v. Sitzmann and Hershel Raff and Michael Breslow},
  journal={The American journal of physiology},
  year={1997},
  volume={272 2 Pt 2},
  pages={R557-62}
}
The adrenergic, respiratory, and cardiovascular responses to isolated core cooling were assessed in awake human subjects. Mild core hypothermia was induced by intravenous infusion of 30 or 40 ml/kg of cold saline (4 degrees C) on 2 separate days. A warm intravenous infusion (30 ml/kg, 37 degrees C) was given on a third day as a control treatment. Mean norepinephrine concentration increased 400% and total body oxygen consumption increased 30% when core temperature decreased 0.7 degrees C. Mean… CONTINUE READING
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